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KMID : 1134120070100030199
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Journal of Breast Cancer
2007 Volume.10 No. 3 p.199 ~ p.205
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The Clinical Characteristics and Outcome of Breast Cancer Patients Older than 70 Years
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Lee Jung-Sun
Ahn Sei-Hyun
Ahn Seung-Do
Son Byung-Ho
Kim Hee-Jung
Hong Soo-Jung
Kim Sung-Bae
Ahn Jin-Hee
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Abstract
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Purpose: There is no concensus on the type of therapy useful for elderly cancer patients. Since 2000, Korea has become an elderly society. This study aims to assess clini- cal characteristics of elderly breast cancer women, and to evaluate determinants and effects of treatment choice for breast cancer prognosis among elderly patients.
Method: We reviewed the clinical reports of 123 breast cancer patients aged ≥70 yr recorded at the Asan Medical Center Breast Cancer Registry between 1992 and 2002. Patient and tumor chariteristics, comorbidity, surgical me- thod, adjuvant therapy and cause of death were taken into consideration. Survival analysis was determined according to the treatment method.
Results: The median time to diagnosis was 33.6 months. Only 9 patients (5.1%) were diagnosed in the screening program. A modified radical mastectomy was performed for 74 patients (60.1%), Breast conserving surgery was per- formed for 26 patients (24.7%), and there was no further curative therapy for 12 patients (9.7%). 32 patients (38.1%) had axillary lymph node metastasis. The median follow-up duration was 43.1 months; the overall survival rate was 71.8%, and the disease free survival rate was 65.4%. Breast cancer related mortality was 62.8%.
Conclusions: Delayed diagnosis and infrequent screening were frequent among elderly patients. Cancer related mor- bidity was less than general breast cancer patients. Treat- ment needs to be adapted to the general health status of the patient and comorbid conditions, but has to offer the best chance of cure, regardless of age.
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KEYWORD
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Elderly women, Breast cancer, Adjuvant therapy
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